Taipei Medical University (TMU) has been a leader in Taiwan’s healthcare system for more than half a century. Around 6,000 students from over 40 countries are currently enrolled in TMU’s 11 colleges. TMU leads in many research areas including cancer, translational medicine, neuroregenerative medicine, biomedical devices and tissue engineering, reproductive medicine and biomedical informatics. As one of the capital city region’s largest health care systems, TMU’s 3 affiliated hospitals–TMU Hospital, Wan Fang Hospital, and Shuang Ho Hospital–are all accredited by Joint Commission International (JCI) to guarantee world-class standards and practices, providing ample opportunities for professional skills training and research. TMU academic programs have grown with the university’s commitment to health service in local communities, with recently-established colleges accepting applicants in biomedical engineering, big data in healthcare, and food safety programs. The permanent appointment of the university’s medical teams to assist the Kingdom of eSwatini and the Marshall Islands provides a unique opportunity for service and education, as well as enhancing Taiwan’s health diplomacy. TMU’s commitment to internationalization has resulted in over 40,000 alumni working to improve healthcare systems in 70 countries around the world. As the university approaches its seventh decade, TMU continues to change and advance in global rankings that have placed it at the front of Taiwan’s private universities in health and science programs.